Epidemiology, management, and risk factors for death of invasive Candida infections in critical care: A multicenter, prospective, observational study in France (2005–2006)

Olivier Leroy, Jean‐Pierre Gangneux, Philippe Montravers, Jean‐Paul Mira, F. Gouin, Jean-Pierre Sollet, Jean Carlet, Jacques Reynes, M. Rosenheim, B. Régnier,

Critical Care Medicine · 2009 · 529 citations · 34 references

Abstract

More than two thirds of patients with invasive candidiasis in ICU present with candidemia. Non-albicans Candida species reach almost half of the Candida isolates. Reduced susceptibility to fluconazole is observed in 17.1% of Candida isolates. Mortality of invasive candidiasis in ICU remains high.

References

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