Science · 1974 · 642 citations · 7 references
Life SciencesBiochemistryEnvironmental SciencesEcotoxicologyEnvironmental ToxicologyMechanisms Of ToxicityBiogeochemical CyclesBiogeochemical CyclingDetoxification PathwaysElemental CyclesHeavy Metal BioaccumulationMicrobial Biogeochemical CyclesElemental Mercury ToxicityMercury BiogeochemistryMercury CycleMercury DetoxificationMercury Toxicity MechanismsMicrobial Mercury Cycling
Some of the chemical and biochemical transformations of toxic elements in the environment are discussed with special emphasis on the role played by microorganisms. When confronted with a toxic substance, microorganisms frequently adapt to detoxify it. However, the detoxification of a substance by microorganisms can yield a product that is either more or less toxic to higher organisms. The detoxification mechanisms of mercury are used as examples to demonstrate that there are biological cycles for the synthesis and degradation of toxic compounds. It is also shown that our present knowledge of the biologial cycles of toxic elements enables us to predict the behavior of other toxic elements in the environment.
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Biosynthesis of dimethylarsine by methanobacterium
B C McBride, R. S. Wolfe · Biochemistry · 1971 · 395 citations
Methylmercury: Bacterial Degradation in Lake Sediments
William J. Spangler, James L. Spigarelli, Joseph M. Rose et al. · Science · 1973 · 155 citations
Methylation of mercury compounds by methylcobalamin
Halina Y. Neujahr, Leif Bertilsson · Biochemistry · 1971 · 134 citations