SIMPLE NON-INVASIVE METHOD TO OBTAIN DNA FOR GENE ANALYSIS

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

Randall K. Saiki, David H. Gelfand, Susanne Stoffel et al. · Science · 1988 · 17.2K citations

Life Sciences, Biotechnology, Molecular Biology +12

Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia

Randall K. Saiki, Stephen J. Scharf, Fred Faloona et al. · Science · 1985 · 9K citations

Medicine, Genetics, Molecular Genetics +17

An Improved Method for Prenatal Diagnosis of Genetic Diseases by Analysis of Amplified DNA Sequences

Scott C. Kogan, Marie Doherty, Jane Gitschier · New England Journal of Medicine · 1987 · 806 citations

Life Sciences, Genetics, Obstetrics +10

Direct Cloning and Sequence Analysis of Enzymatically Amplified Genomic Sequences

Stephen J. Scharf, Glenn T. Horn · Science · 1986 · 758 citations

Life Sciences, Genetics, Molecular Biology +16

A candidate for the cystic fibrosis locus isolated by selection for methylation-free islands

Xavier Estivill, Martin Farrall, Peter Scambler et al. · Nature · 1987 · 336 citations

Life Sciences, Genetics, Molecular Genetics +13