Concepedia

Pancreatic Islet-Acinar Cell Interaction: Amylase Messenger RNA Levels Are Determined By Insulin

Murray Korc, David Owerbach, Carmen Quinto, William J. Rutter

Science · 1981 · 275 citations · 20 references

DOI

Concepts

Abstract

Pancreatic amylase messenger RNA progressively decreases in rats rendered diabetic with streptozotocin. Insulin reverses this effect, inducing a selective decrease in amylase messenger RNA in the pancreas. Parotid amylase messenger RNA is not significantly affected by either diabetes or insulin.

References

20

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

John M. Chirgwin, Alan Przybyla, Raymond J. MacDonald et al. · Biochemistry · 1979 · 22.2K citations

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Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

Peter Rigby, Marianne Dieckmann, Carl Rhodes et al. · Journal of Molecular Biology · 1977 · 11.7K citations

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A membrane-filter technique for the detection of complementary DNA

David T. Denhardt · Biochemical and Biophysical Research Communications · 1966 · 3.9K citations

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Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate.

Geoffrey M. Wahl, Michael Stern, George R. Stark · Proceedings of the National Academy of Sciences · 1979 · 3.4K citations · Full text

, , +13

A new method for the determination ofα-amylase

H. Rinderknecht, Peter Wilding, Bernard J. Haverback · Cellular and Molecular Life Sciences · 1967 · 309 citations · Full text

, , +9