Roux-en-Y Gastric Bypass Reduces Lipid Overaccumulation in Liver by Upregulating Hepatic Autophagy in Obese Diabetic Rats

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

The EMBO Journal · 2000 · 6.5K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +11

Autophagy fights disease through cellular self-digestion

Noboru Mizushima, Beth Levine, Ana María Cuervo et al. · Nature · 2008 · 6.4K citations · Full text

Life Sciences, Biochemistry, Cell Biology +14

Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp.

Masafumi Matsuda, Ralph A. DeFronzo · Diabetes Care · 1999 · 5.6K citations

Medicine, Endocrinology, Internal Medicine +12

Autophagy regulates lipid metabolism

Rajat Singh, Susmita Kaushik, Yongjun Wang et al. · Nature · 2009 · 3.9K citations · Full text

Life Sciences, Biochemistry, Cell Biology +12

Combination of high-fat diet-fed and low-dose streptozotocin-treated rat: A model for type 2 diabetes and pharmacological screening

K. K. Srinivasan, Bhoomi Viswanad, Lydia Asrat et al. · Pharmacological Research · 2005 · 1.9K citations

Medicine, Endocrinology, Pharmacology +10