Brain Energy Metabolism in Patients With Spontaneous Subarachnoid Hemorrhage and Global Cerebral Edema

Abstract

Patients with global cerebral edema have higher interstitial levels of lactate and pyruvate. The edema group may have developed a cerebral hypermetabolism to meet the increased energy demand in the recovery phase after SAH. This stress would make the brain more vulnerable to secondary insults, increasing the likelihood of energy failure.