Bone Marrow Cells Immunomagnetically Selected For CD271+ Antigen Promote <i>In Vitro</i> the Repair of Articular Cartilage Defects

Abstract

Synovial membranes from OA patients contain more cells expressing CD271 antigen than those from healthy joints, and spontaneous cartilage repair tissue contains cells positive for CD271 antigen. These data suggest the involvement of CD271 antigen in spontaneous cartilage repair and indicate that the cell subset MSC CD271+ provides higher quality chondral repair than the CD271- subset.