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Facile Syntheses of Azetidin-3-ols by Rearrangement of 2,3-Epoxypropylamines
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Citations
11
References
2003
Year
Upon TreatmentEngineeringEnantioselective SynthesisFacile SynthesesOrganic ChemistryFour-membered RingsStereoselective SynthesisChemistrySynthetic ChemistryBiomolecular EngineeringPrimary Alkylamines
Abstract The N-alkyl-2,3-epoxypropylamines (2) formed from primary alkylamines (1) and epichlorohydrin were chemoselectively rearranged to the four-membered rings, N-alkylazetidin-3-ols (3), upon treatment of triethylamine in refluxing acetonitrile.
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