<i>Pseudomonas aeruginosa</i> Lipopolysaccharide Induces Osteoclastogenesis Through a Toll‐Like Receptor 4 Mediated Pathway in Vitro and in Vivo

Abstract

P. aeruginosa LPS acts indirectly through osteoblasts to induce bone resorption. Optimal osteoclastogenesis in vitro required functional TLR4 expression in both BMMs and osteoblasts.