Probing Secondary Carbohydrate−Protein Interactions with Highly Dense Cyclodextrin-Centered Heteroglycoclusters: The Heterocluster Effect

Abstract

Comparison of the lectin-binding properties for highly dense beta-cyclodextrin-centered homo- and heteroglycoclusters with defined architecture provides evidence for the existence of strong synergic effects (heterocluster effect) on carbohydrate-protein recognition events.