Journal of Cancer Research and Therapeutics · 2009 · 38 citations · 16 references
MedicineOncologySurgeryChemotherapyMedical OncologyNeuro-oncologyBrain TumorsCorpus CallosotomyGlioblastomaGlioma RadiotherapyRadiation TherapyConcomitant TherapyGlioblastoma ChemotherapyGlioblastoma SurgeryGlioma ChemotherapyGlioma SurgeryRadiation Therapy Combinations
The prognosis of glioblastoma multiforme (GBM) is poor even with aggressive first-line therapy, which includes surgery, radiation therapy, and adjuvant chemotherapy. Although the ideal course of treatment for elderly patients with newly diagnosed GBM is still undecided and requires further studies, the new chemotherapeutic agents administered with or without concomitant radiation therapy have shown promising results. However, in our setting, where resources are limited and newer treatment options are expensive, it is often difficult to deliver the best care to the patient.
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Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma
Roger Stupp, Warren Mason, Martin J. van den Bent et al. · New England Journal of Medicine · 2005 · 21.6K citations · Full text
Roger Stupp, Pierre-Yves Dietrich, Sandrine Ostermann Kraljevic et al. · Journal of Clinical Oncology · 2002 · 815 citations
Multicenter phase II trial of temozolomide in patients with glioblastoma multiforme at first relapse
M. Brada, Khê Hoang‐Xuan, R. Rampling et al. · Annals of Oncology · 2001 · 372 citations · Full text
Medicine, Oncology, Pharmacology +15