Apo-Ghrelin Receptor Forms Heteromers with DRD2 in Hypothalamic Neurons and Is Essential for Anorexigenic Effects of DRD2 Agonism

Ghrelin is a growth-hormone-releasing acylated peptide from stomach

Masayasu Kojima, Hiroshi Hosoda, Yukari Date et al. · Nature · 1999 · 8.5K citations

Life Sciences, Biochemistry, Endocrinology +10

Ghrelin Enhances Appetite and Increases Food Intake in Humans

Alison Wren, Leighton Seal, Mark A. Cohen et al. · The Journal of Clinical Endocrinology & Metabolism · 2001 · 2.4K citations · Full text

Life Sciences, Endocrinology, Physiology +16

A Receptor in Pituitary and Hypothalamus That Functions in Growth Hormone Release

Andrew D. Howard, Scott D. Feighner, Doris Cully et al. · Science · 1996 · 2.1K citations

Medicine, Endocrinology, Pharmacology +17

The Distribution and Mechanism of Action of Ghrelin in the CNS Demonstrates a Novel Hypothalamic Circuit Regulating Energy Homeostasis

Michael A. Cowley, Roy G. Smith, Sabrina Diano et al. · Neuron · 2003 · 1.7K citations · Full text

Life Sciences, Endocrinology, Neuroscience +10

Dopamine D2 receptors in addiction-like reward dysfunction and compulsive eating in obese rats

Paul M. Johnson, Paul J. Kenny · Nature Neuroscience · 2010 · 1.5K citations · Full text

Medicine, Neuroscience, Pharmacology +17