Does carcinogenic potency correlate with mutagenic potency in the Ames assay?

Methods for detecting carcinogens and mutagens with the salmonella/mammalian-microsome mutagenicity test

Bruce N. Ames, Joyce McCann, Edith F. Yamasaki · Mutation Research/Environmental Mutagenesis and Related Subjects · 1975 · 7.4K citations

Pharmacy, Toxicology, Carcinogenesis +7

Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals.

Joyce McCann, E Choi, Edna N. Yamasaki et al. · Proceedings of the National Academy of Sciences · 1975 · 3.3K citations · Full text

Pharmacy, Environmental Sciences, Toxicology +16

Metabolic activation of benzo(a)pyrene proceeds by a diol-epoxide

Peter Sims, P.L. Grover, Alan Swaisland et al. · Nature · 1974 · 1.1K citations

Life Sciences, Biochemistry, Metabolism +12

Progress in Genetic Toxicology

Diana C. Anderson · FEBS Letters · 1978 · 580 citations

Pharmacy, Genetics, Toxicology +3

Evaluation of six short term tests for detecting organic chemical carcinogens and recommendations for their use

I. F. H. Purchase, E. Longstaff, John Ashby et al. · Nature · 1976 · 277 citations

Pharmacy, Clinical Toxicology, Toxicology +8