A Long-term View of Bacterial Endocarditis

Abstract

Article1 August 1965A Long-term View of Bacterial Endocarditis337 Cases 1924 to 1963S. RABINOVICH, M.D., J. EVANS, M.D., I. M. SMITH, M.D., F.A.C.P., M.R.C.P. (GLAS.), L. E. JANUARY, M.D., F.A.C.P.S. RABINOVICH, M.D.Search for more papers by this author, J. EVANS, M.D.Search for more papers by this author, I. M. SMITH, M.D., F.A.C.P., M.R.C.P. (GLAS.)Search for more papers by this author, L. E. JANUARY, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-63-2-185 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptWith the advent of chemotherapy and antibiotics, the perspective of bacterial endocarditis changed radically. A disease that was uniformly fatal became a serious disease that could be cured. With potentially effective treatment an early and accurate diagnosis improved the prognosis. Many aspects of the clinical features and the type of bacteria responsible for the endocarditis are not found in the same proportions as before the era of antibiotics. At the University of Iowa Hospitals there has been a continuing interest in bacterial endocarditis since 1924 (1-5); therefore, we have available at one institution an unusually large number of cases for...References1. HARDIN RC: The variability of embolic phenomena in subacute bacterial endocarditis. J. Iowa Med. Soc. 31, 95, 1941. Google Scholar2. THEILENJANUARY ELE: The treatment of subacute bacterial endocarditis. J. Iowa Med. Soc. 42: 167, 1952. MedlineGoogle Scholar3. DE GOWINCARTERBORTS ELJRIH: A case of infection with Brucella suis causing endocarditis and nephritis; death from rupture of mycotic aneurysm. Amer. Heart J. 30: 77, 1945. CrossrefGoogle Scholar4. DE GOWIN EL: Permanent residual damage in patients recovering from subacute bacterial endocarditis. Proc. Cent. Soc. Clin. Res. 18: 39, 1945. 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SMITHVICKERSWILLIS IMABP: The natural history of 338 treated and untreated patients with staphylococcal septicemia (1936-1955). Lancet 1: 1318, 1960. CrossrefMedlineGoogle Scholar13. LINDEHEINS LMHL: Bacterial endocarditis following surgery for congenital heart disease. New Eng. J. Med. 236: 65, 1960. CrossrefGoogle Scholar14. ANDREASSENJENSEN RNK: Bacterial endocarditis following mitral valvotomy. Ann. Intern. Med. 45: 534, 1956. LinkGoogle Scholar15. BAILEYBOLTONREDONDO-RAMIREZ CPHEHP: Surgery of the mitral valve. Surg. Clin. N. Amer. 32: 1807, 1952. CrossrefGoogle Scholar16. KOIWAINAHAS EKHC: Subacute bacterial endocarditis following cardiac surgery. Arch. Surg. (Chicago) 73: 272, 1956. CrossrefGoogle Scholar17. BASHOURWINCHELL FACP: Right sided endocarditis. Amer. J. Med. Sci. 240: 411, 1960. CrossrefMedlineGoogle Scholar18. BELLIWAISBREN JBA: The number of blood cultures necessary to diagnose most cases of bacterial endocarditis. Amer. J. Med. Sci. 232. 284, 1956. CrossrefMedlineGoogle Scholar19. PANKEY GA: Acute bacterial endocarditis at the University of Minnesota Hospitals 1939-1959. Amer. Heart J. 64: 583, 1962. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: S. RABINOVICH, M.D.; J. EVANS, M.D.; I. M. SMITH, M.D., F.A.C.P., M.R.C.P. (GLAS.); L. E. JANUARY, M.D., F.A.C.P.Affiliations: Iowa City, IowaFrom the Department of Medicine, Infectious Disease Division, University of Iowa Hospitals, Iowa City, Iowa.This work was supported by grant AI 04046 from the National Institute of Allergy and Infectious Diseases, U. S. Public Health Service, Bethesda, Md.Requests for reprints should be addressed to Ian Maclean Smith, M.D., Department of Medicine, Infectious Disease Division, University of Iowa Hospitals, Iowa City, Iowa 52241. 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