Hydroamination of Alkynes Catalyzed by Imido Complexes of Titanium and Vanadium

Abstract

Intermolecular alkyne hydroamination with primary amines is catalyzed with group 5\n(vanadium and tantalum) transition metal complexes and a new imido-Ti(IV) complex. The\nreaction is very regioselective. The scope of the reaction was investigated with a variety of\nalkynes and amines; 1-hexyne and anilines were found to be especially good substrates.