Propofol Induces Changes in the Cytosolic Free Calcium Concentration and the Cytoskeletal Organization of Cultured Human Glial Cells and Primary Embryonic Rat Brain Cells

Abstract

Propofol induced changes in the cytoskeletal organization of actin in cultured rat neurons and human glial cells. These changes must have been due to the increase in intracellular calcium seen shortly after the addition of propofol, since no effects on actin organization were seen when intracellular calcium was depleted.