Clinical and biological implications of CD133-positive and CD133-negative cells in glioblastomas

Identification of human brain tumour initiating cells

Sheila K. Singh, Cynthia Hawkins, Ian D. Clarke et al. · Nature · 2004 · 7.4K citations

Medicine, Cancer Biology, Oncology +11

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

Shideng Bao, Qiulian Wu, Roger E. McLendon et al. · Nature · 2006 · 6.4K citations

Medicine, Cancer Biology, Oncology +16

Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis

Heidi Phillips, Samir Kharbanda, Ruihuan Chen et al. · Cancer Cell · 2006 · 3.2K citations · Full text

Medicine, Neuroscience, Oncology +16

Isolation and Characterization of Tumorigenic, Stem-like Neural Precursors from Human Glioblastoma

Rossella Galli, Elena Binda, Ugo Orfanelli et al. · Cancer Research · 2004 · 2.6K citations · Full text

Life Sciences, Neuroscience, Oncology +15

Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines

Jeongwu Lee, Svetlana Kotliarova, Yuri Kotliarov et al. · Cancer Cell · 2006 · 2.3K citations · Full text

Medicine, Cell Biology, Oncology +16