Concepedia

Quick identification of apoptosis inducer from Isodon eriocalyx by a drug discovery platform composed of analytical high-speed counter-current chromatography and the fluorescence-based caspase-3 biosensor detection

Quan‐Bin Han, Ting Yu, Fanny Lai, Yan Zhou, Chao Feng, Weina Wang, Xiaohui Fu, Clara Bik‐San Lau, Kathy Qian Luo, Hong‐Xi Xu

Talanta · 2010 · 28 citations · 15 references

Concepts

Life SciencesCell BiologyPharmacologyApoptosisBiosensorsDrug DiscoveryApoptotic Signal TransductionApoptotic SignalingCaspase ActivationElectrochemical BiosensorsExtrinsic Apoptotic PathwaySignal DetectionApoptosis BiomarkersApoptosis Signaling PathwaysCell Death AssaysCell Death DetectionDrug-induced ApoptosisFluorescence Imaging Probes

References

15

High-speed countercurrent chromatography

Yoichiro Ito, Walter D. Conway · C R C Critical Reviews in Analytical Chemistry · 1986 · 290 citations

Pharmacy, Chemical Engineering, Chemistry +10

High-Speed Countercurrent Chromatography

Yoichiro Ito, Walter D. Conway · Critical Reviews in Analytical Chemistry · 1986 · 279 citations

The Coil Planet Centrifuge

Yukishige Ito, M. Weinstein, Ichiro Aoki et al. · Nature · 1966 · 212 citations

Engineering, Electrical Engineering, Electromagnetics +1

A phase II study of taxol in patients with malignant melanoma

Avi I. Einzig, H HOCHSTER, P H Wiernik et al. · Investigational New Drugs · 1991 · 181 citations

Medicine, Oncology, Pharmacology +14

Eriocalyxin B induces apoptosis of t(8;21) leukemia cells through NF-κB and MAPK signaling pathways and triggers degradation of AML1-ETO oncoprotein in a caspase-3-dependent manner

L. Wang, W-L Zhao, J-S Yan et al. · Cell Death and Differentiation · 2006 · 120 citations

Life Sciences, Cancer Biology, Oncology +13