European Neurology · 2008 · 18 citations · 0 references
MedicineNeurosurgeryPathologyMetastasisNeoplasiaNeuro-oncologyBrain MetastasesBrain MetastasisBrain TumorsCentral Nervous System TumorsLeptomeningeal DiseaseIntracranial MetastasesIntracranial NeoplasiaLeptomeningeal Metastasis Involving Cranial NervesLeptomeningeal SpreadLocal Tumor RecurrenceOlfactory Epithelium Pathology
Esthesioneuroblastoma is a rare neoplasm of neuroectodermal origin, arising from the olfactory epithelium in the roof of the nasal cavity. Extension to the brain can occur less frequently than local recurrence, but leptomeningeal metastases without brain involvement have rarely been mentioned. We report 2 cases with poor prognosis of leptomeningeal infiltration during the evolution of esthesioneuroblastoma.