High Body Mass Index After Age 20 and Diabetes Mellitus Are Independent Risk Factors for Ossification of the Posterior Longitudinal Ligament of the Spine in Japanese Subjects

Abstract

Excessive weight gain between 20 and 40 years of age, diabetes mellitus, and lumbago were found to be independent risk factors for ossification of the posterior longitudinal ligament of the spine. Follow-up studies, including the addition of hospital-based control participants and analysis of genetic polymorphisms, will be needed in the future.