The <i>EML4‐ALK</i> fusion gene is involved in various histologic types of lung cancers from nonsmokers with wild‐type <i>EGFR</i> and <i>KRAS</i>

Abstract

The EML4-ALK fusion gene was present in various histologic types of NSCLC. It occurred in mutual exclusion to EGFR and KRAS mutations and was associated with nonsmokers. The authors concluded that EML4-ALK may be useful for predicting the potential response to ALK inhibitors as a therapeutic option for patients with lung cancer.