Evidence for mediation by 5-HT2 receptors of 5-hydroxytryptamine-induced contraction of canine basilar artery

Multiple Serotonin Receptors: Differential Binding of [3H]5-Hydroxytryptamine, [3H]Lysergic Acid Diethylamide and [3H]Spiroperidol

Stephen J. Peroutka, Solomon H. Snyder · Molecular Pharmacology · 1979 · 1.4K citations

Medicine, Neuroscience, Pharmacology +15

Cumulative dose-response curves. II. Technique for the making of dose-response curves in isolated organs and the evaluation of drug parameters.

J. M. van Rossum · PubMed · 1963 · 1.2K citations

Pharmacy, Pharmacokinetics, Pharmacology +14

[3H]Ketanserin (R 41 468), a selective 3H-ligand for serotonin2 receptor binding sites. Binding properties, brain distribution, and functional role.

J E Leysen, C. J. E. Niemegeers, Jan M. Van Nueten et al. · Molecular Pharmacology · 1982 · 1.1K citations

Medicine, Medicinal Chemistry, Pharmacology +17

Vascular effects of ketanserin (R 41 468), a novel antagonist of 5-HT2 serotonergic receptors.

Jan M. Van Nueten, P A Janssen, Johan van Beek et al. · Journal of Pharmacology and Experimental Therapeutics · 1981 · 524 citations

Medicine, Medicinal Chemistry, Pharmacology +14

(�)[125Iodo]cyanopindolol, a new ligand for ?-adrenoceptors: Identification and quantitation of subclasses of ?-adrenoceptors in guinea pig

G�nter Engel, Daniël Hoyer, R. Berthold et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 1981 · 390 citations

Medicine, Pharmacology, Biochemical Pharmacology +7