Highly Enantio‐ and Diastereoselective Construction of 1,2‐Disubstituted Cyclopentane Compounds by Dirhodium(II) Tetrakis[<i>N</i>‐phthaloyl‐(<i>S</i>)‐<i>tert</i>‐leucinate]‐Catalyzed CH Insertion Reactions of α‐Diazo Esters

Abstract

Abstract A highly enantio‐ and diastereoselective intramolecular CH insertion reaction of α‐diazo esters has been achieved with the use of dirhodium(II) tetrakis[ N ‐phthaloyl‐( S )‐ tert ‐leucinate] as a catalyst, providing exclusively cis ‐2‐arylcyclopentane‐1‐carboxylates in up to 95% ee with no evidence of alkene formation.