ELEVATION OF URIC ACID CLEARANCE CAUSED BY INAPPROPRIATE ANTIDIURETIC HORMONE SECRETION

Abstract

Abstract. Two patients with hyponatraemia resulting from an inappropriate ADH secretion syndrome had low serum values and elevated clearances of uric acid. All the values returned to normal after fluid restriction. The same changes in uric acid clearance and serum level were seen when this syndrome was experimentally induced in five normal subjects.