Positron Emission Tomography Imaging with 18F-Labeled Z <i>HER2:2891</i> Affibody for Detection of HER2 Expression and Pharmacodynamic Response to HER2-Modulating Therapies - Concepedia

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Positron Emission Tomography Imaging with 18F-Labeled Z <i>HER2:2891</i> Affibody for Detection of HER2 Expression and Pharmacodynamic Response to HER2-Modulating Therapies

DOI Full Paper Access

34

Citations

35

References

2014

Year

Sebastian Trousil, Susan Hoppmann, Quang‐Dé Nguyen, Maciej Kaliszczak, Giampaolo Tomasi, P.B. Iveson, Duncan Hiscock, Eric O. Aboagye

Clinical Cancer Research

Abstract

[(18)F]GE-226 binds with high specificity to HER2 independent of cell lineage. The tracer has potential utility for HER2 detection, irrespective of prior trastuzumab treatment, and to discern HSP90 inhibitor-mediated HER2 degradation.

References

	Year	Citations

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