B Cells Play an Important Role in Lipopolysaccharide-Induced Bone Resorption

Osteoprotegerin Ligand Is a Cytokine that Regulates Osteoclast Differentiation and Activation

David L. Lacey, Emma Timms, Hong‐Lin Tan et al. · Cell · 1998 · 5.5K citations · Full text

Medicine, Cell Biology, Bone Metabolism +13

Osteoprotegerin: A Novel Secreted Protein Involved in the Regulation of Bone Density

W. Scott Simonet, Dave Lacey, Colin R. Dunstan et al. · Cell · 1997 · 5.1K citations · Full text

Medicine, Biochemistry, Molecular Biology +13

Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL

Hisataka Yasuda, Nobuyuki Shima, N. Nakagawa et al. · Proceedings of the National Academy of Sciences · 1998 · 4.3K citations

Medicine, Cell Biology, Molecular Biology +15

TNF-α induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand

Jonathan Lam, Sunao Takeshita, Jane E. Barker et al. · Journal of Clinical Investigation · 2000 · 1.4K citations · Full text

Life Sciences, Cell Biology, Immunology +17

T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γ

Hiroshi Takayanagi, Kouetsu Ogasawara, Shigeaki Hida et al. · Nature · 2000 · 1.4K citations

Medicine, Cell Biology, Immunology +12