Fluidized bed spray granulation: analysis of heat and mass transfers and dynamic particle populations

Abstract

A model was developed taking into consideration the heat and mass transfer processes in liquid-sprayed fluidized beds. Such fluidized beds (FB) are used for granulation, coating and agglomeration. Conclusions are drawn on the relevance of particle dispersion, spraying and drying to temperature and concentrations distributions. In extension, the model was coupled with a population balance model to describe the particle size distribution and the seeds formation for continuous external FBSG (fluidized bed spray granulation) with non-classifying product discharge and a screening and milling unit in the seeds recycle. The effects of seeds formation on the stability of the process is discussed.