Cytokine, Sickness Behavior, and Depression

Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice

Jason C. O’Connor, Mark A. Lawson, Caroline André et al. · Molecular Psychiatry · 2008 · 1.3K citations · Full text

Medicine, Neuroscience, Pharmacology +14

Toll-Like Receptor Signaling Pathways

Gregory M. Barton, Ruslan Medzhitov · Science · 2003 · 1.3K citations

Life Sciences, Immunology, Microbiology +16

Corticotropin-Releasing Factor-Producing Neurons in the Rat Activated by Interleukin-1

F. Berkenbosch, Joep van Oers, Adriana del Rey et al. · Science · 1987 · 1.2K citations

Life Sciences, Endocrinology, Neuroscience +17

Etanercept and clinical outcomes, fatigue, and depression in psoriasis: double-blind placebo-controlled randomised phase III trial

Stephen K. Tyring, Alice B. Gottlieb, Kim Papp et al. · The Lancet · 2005 · 1.1K citations

Medicine, Dermatology, Pharmacotherapy +6

Exaggerated neuroinflammation and sickness behavior in aged mice after activation of the peripheral innate immune system

Jonathan P. Godbout, J. Chen, J. Abraham et al. · The FASEB Journal · 2005 · 812 citations

Life Sciences, Immunology, Neuroscience +17