Spontaneous Inflammatory Bowel Disease in Multiple Mutant Mouse Lines: Association with Colonization by <i>Helicobacter hepaticus</i>

Abstract

The presence of H. hepaticus in association with IBD in multiple lines of genetically altered mice suggests further studies are needed to test experimentally the role H. hepaticus plays in the development of IBD in susceptible mice. Additionally, specific mutant mouse lines infected with H. hepaticus in this study may provide additional models for elucidation of microbial and genetic factors in the pathogenesis of IBD.