Magnetic Resonance Imaging-Based Volumetric Analysis of Basal Ganglia Nuclei and Substantia Nigra in Patients with Parkinson’s Disease

Abstract

Magnetic resonance imaging-based volumetric measurement is a sensitive method in the assessment of morphological changes of PD in vivo. The putamen atrophy was correlated with the severity of clinical findings. The volumetric measurement of putamen could potentially be a useful indicator of PD in the early stage.