Utility of thieno[2,3-b] pyridine derivatives in the synthesis of some condensed heterocyclic compounds with expected biological activity

Abstract

Introduction The thieno[2,3-b]pyridine derivatives occupy special place and have attracted considerable attention because of their broad pharmacological activities, including anticancer [1-9], antiviral [10-13], anti-inflammatory [14-17], antimicrobial [18,19], antidiabetic [20-23], antihypertensive [24-26] and osteogenic [27,28] activities, in addition to treatment of CNS disorders [29-31]. The aforementioned biological activities stimulated our interest for the