Bulletin of the Chemical Society of Japan · 2011 · 16 citations · 12 references
Natural SciencesBiochemistryCancer BiologyCancer PharmacologyCoral Reef BiologyCoral Reef EcologyMarine Bioactive CompoundsMarine Natural ProductsReef-building Coral BiologyReef-building CoralsBioactive Compounds From Marine CoralsBioactive Marine MetabolitesMarine Sponge MetabolitesMarine-derived Anticancer CompoundsSecondary MetabolitesSoft Coral BiologySoft Coral MetabolitesSponges-derived Metabolites
Abstract Two new hydroxycembranes 1 and 2 and two known epoxycembrane 3 and isocembrol 4 have been isolated from a Formosan soft coral Sinularia facile. The structures of new metabolites were elucidated on the basis of extensive spectroscopic analysis and cytotoxic activity of 1–4 against the proliferation of a limited panel of cancer cell lines was measured.
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Sean M. Kerwin · Journal of the American Chemical Society · 2010 · 130 citations