A Copper(I)‐Catalyzed Three‐Component Domino Process: Assembly of Complex 1,2,3‐Triazolyl‐5‐Phosphonates from Azides, Alkynes, and <i>H</i>‐Phosphates

Abstract

Three is better than one! A new copper-catalyzed tricomponent reaction of a terminal alkyne, organic azide, and H-phosphate (CuAA[P]C) leads to a structurally diverse polysubstituted 1,2,3-triazolyl-5-phosphonate, which provides an efficient tool for the direct introduction of phosphonic acid groups by a "click reaction".