Concepedia

bcl-2/bax ratio as a predictive marker for therapeutic response to radiotherapy in patients with prostate cancer

Timothy J. Mackey, Andrew Borkowski, Pradip Amin, Stephen C. Jacobs, Natasha Kyprianou

Urology · 1998 · 193 citations · 30 references

DOI

Concepts

References

30

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death

Zoltán N. Oltval, Curt Milliman, Stanley J. Korsmeyer · Cell · 1993 · 6K citations

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Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

Toshiyuki Miyashita, John C. Reed · Cell · 1995 · 4.1K citations · Full text

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Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

David M. Hockenbery, Gabriel Núñez, Curt Milliman et al. · Nature · 1990 · 3.8K citations

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Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo.

Toshiyuki Miyashita, Stanisław Krajewski, Maryla Krajewska et al. · PubMed · 1994 · 2.2K citations

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Cancer statistics, 1995

Phyllis A. Wingo, T. Tong, S. Bolden · CA A Cancer Journal for Clinicians · 1995 · 1.4K citations · Full text

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