Preparation of [18F]fluoromisonidazole by nucleophilic substitution on THP-protected precursor: Yield dependence on reaction parameters

Efficient stereospecific synthesis of no-carrier-added 2-[18F]-fluoro-2-deoxy-D-glucose using aminopolyether supported nucleophilic substitution.

K. Hamacher, Heinz H. Coenen, G. Stöcklin · PubMed · 1986 · 1.4K citations

Life Sciences, Biochemistry, Metabolism +9

Synthesis and biodistribution of 18F-labeled fluoronitroimidazoles: Potential in vivo markers of hypoxic tissue

Paul Jerabek, Timothy B. Patrick, Michael R. Kilbourn et al. · International Journal of Radiation Applications and Instrumentation Part A Applied Radiation and Isotopes · 1986 · 131 citations

Medicine, Pharmacokinetics, Pharmacology +11

A radiosynthesis of fluorine-18 fluoromisonidazole.

John R. Grierson, Jeanne M. Link, Chester A. Mathis et al. · PubMed · 1989 · 130 citations

Natural Sciences, Chemistry, Nuclear Chemistry +8

An efficient radiosynthesis of [18F]fluoromisonidazole

Jean-Luc Lim, Marc S. Berridge · Applied Radiation and Isotopes · 1993 · 116 citations

Medicine, Pharmacology, Radiology +6

No-carrier-added synthesis of 3-[18F]fluoro-1-(2-nitro-1-imidazolyl)-2-propanol. A potential PET agent for detecting hypoxic but viable tissues

Dah‐Ren Hwang, Carmen S. Dence, Thomas A. Bonasera et al. · International Journal of Radiation Applications and Instrumentation Part A Applied Radiation and Isotopes · 1989 · 36 citations

Medicine, Nuclear Medicine, Molecular Imaging +14