New England Journal of Medicine · 1980 · 46 citations · 20 references
Life SciencesEvolutionary BiologyGeneticsEvolutionary GeneticsGenome EvolutionMolecular EvolutionEvolutionGenetic CodeHorizontal Gene TransferMobile Genetic ElementsMolecular AdaptationSequence EvolutionGenetic Mobile ElementsGenomic AdaptationInsertion EvolutionMobile Element InsertionsMolecular Evolutionary Models
The concept that new genes can be inserted into living animals is relatively new, but the phenomenon of transmission of genetic material from one organism into the genome of another has probably existed since the early stages of evolution. Mutation of nucleotide sequences in the DNA code has long been seen as the principal mechanism of evolutionary adaptation, while transmission of genetic materials between species was considered to be a rare event. This conventional view requires revision in the light of recent knowledge about genetic elements adapted for shuttling between different regions of a single genome or between different genomes. . . .
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Transformation of mammalian cells with genes from procaryotes and eucaryotes
Michael Wigler, Raymond W. Sweet, Gek Kee Sim et al. · Cell · 1979 · 1.5K citations
Biochemical transfer of single-copy eucaryotic genes using total cellular DNA as donor
Michael Wigler, Àngel Pellicer, Saul J. Silverstein et al. · Cell · 1978 · 1.3K citations
The Significance of Pneumococcal Types
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The significance of penumococcal types
Fred Griffith · Journal of Hygiene · 1966 · 975 citations · Full text