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Synthesis of benzo[3,4]azepino[1,2-b]isoquinolin-9-ones from 3-arylisoquinolines via ring closing metathesis and evaluation of topoisomerase I inhibitory activity, cytotoxicity and docking study

Medicinal ChemistryHeterocyclicNatural SciencesMedicineDocking StudyOrganic ChemistryChemistryHeterocycle ChemistryPharmacologyPharmaceutical ChemistryDrug DiscoveryNatural Product Synthesis