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SERUM TRANSAMINASE ACTIVITY IN UNCOMPLICATED AND COMPLICATED PREGNANCY AND IN NEWBORNS
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1958
Year
Fetal MedicineGynecologyGlutamic-oxalacetic Transaminase ActivityFetal ComplicationEmbryologyOxidative StressHepatotoxicityMaternal NutritionPublic HealthMaternal Cardiovascular OutcomeLiver PhysiologyMaternal HealthPrenatal DiagnosisMaternal-fetal MedicineEndocrinologyPharmacologyDrug-induced Liver InjuryHepatologyTransaminase ActivityPhysiologyPediatricsPregnancyPregnant WomenMetabolismMedicine
Glutamic-oxalacetic transaminase activity was determined in serum from pregnant women with and without complications (missed abortion, incomplete abortion, complete and threatened abortion, hepatosis, toxemia) and from newborns (umbilical cord blood). The activity was found to be normal in uncomplicated pregnancy, at delivery, in the puerperium, and in different types of abortion, but to be somewhat increased in hepatosis. In toxemia the activity was often markedly increased (30 per cent), but returned to the normal level as the symptoms of toxemia disappeared. This increase in the transaminase activity is possibly due to liver damage.