PKB Inhibition Prevents the Stimulatory Effect of Insulin on Glucose Transport and Protein Translocation but Not the Antilipolytic Effect in Rat Adipocytes

Expression of a Constitutively Active Akt Ser/Thr Kinase in 3T3-L1 Adipocytes Stimulates Glucose Uptake and Glucose Transporter 4 Translocation

Aimee D. Kohn, Scott A. Summers, Morris J. Birnbaum et al. · Journal of Biological Chemistry · 1996 · 1.3K citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas.

J Q Cheng, Andrew K. Godwin, Alfonso Bellacosa et al. · Proceedings of the National Academy of Sciences · 1992 · 738 citations

Medicine, Molecular Biology, Oncology +15

Selective inhibition of catalytic activity of smooth muscle myosin light chain kinase.

M. Saitoh, Tomohiko Ishikawa, S Matsushima et al. · Journal of Biological Chemistry · 1987 · 512 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +7

Up-regulation of Akt3 in Estrogen Receptor-deficient Breast Cancers and Androgen-independent Prostate Cancer Lines

Kaname Nakatani, Devon A. Thompson, Andreas Barthel et al. · Journal of Biological Chemistry · 1999 · 474 citations · Full text

Life Sciences, Molecular Biology, Oncology +15

Requirement for Activation of the Serine-Threonine Kinase Akt (Protein Kinase B) in Insulin Stimulation of Protein Synthesis but Not of Glucose Transport

Tadahiro Kitamura, Wataru Ogawa, Hiroshi Sakaue et al. · Molecular and Cellular Biology · 1998 · 334 citations

Life Sciences, Cell Biology, Endocrinology +15