Accelerated Angiogenic Host Tissue Response to Poly(L-Lactide-co-Glycolide) Scaffolds by Vitalization with Osteoblast-like Cells

Abstract

Our study demonstrates that PLGA scaffold vitalization with OLCs accelerates the angiogenic response in the surrounding host tissue. Bone substitutes created by tissue engineering may thus be superior to nonvitalized substitutes although the seeded cells do not survive for long periods.