Noninvasive Assessment of Hypoxia in Rabbit Advanced Atherosclerosis Using ¹⁸ F-fluoromisonidazole Positron Emission Tomographic Imaging

Abstract

Plaque hypoxia increases with disease progression and is present in macrophage-rich areas associated with neovascularization. (18)F-fluoromisonidazole positron emission tomographic imaging emerges as a new tool for the detection of atherosclerotic lesions.