Chiral Iminospherand of a Tetrahedral Symmetry Spontaneously Assembled in a [6 + 4] Cyclocondensation

Abstract

Thermodynamically driven cyclocondensation of (R,R)-1,2-diaminocyclohexane and 1,3,5-triformylbenzene yields solely a [4 + 6] spherand type product. This is a unique example of spontaneous formation of an organic compound of permanent chiral tetrahedral (T) symmetry.