IEEE Transactions on Biomedical Engineering · 1973 · 20 citations · 11 references
EngineeringBiomedical EngineeringElectrical EngineeringElectrophysiologyLow-power DesignPhysiological Systems ModelingBattery SystemsBattery TechnologyCardiac PacingCardiac PhysiologyElectrochemical CellsEnergy RequirementsCardiac Implantable DevicesCardiac PacemakersMinimum Energy RequirementMinimum-energy ControlPacemaker CellsPacemaker PhysiologyPower RequiredPulse Duration Effects
Batteries that power implanted cardiac pacemakers deteriorate because of energy drain and permeation of body fluids. They must, therefore, be replaced periodically, most often by means of an operation. In this paper, the stimulating waveform that draws the least amount of energy from the battery and also delivers the minimum energy to a heart cell is derived. It is shown that a 31-percent reduction in energy (with respect to that required by the standard rectangular pulse) can be achieved if the pulse duration is about twice the cell time constant. Moreover, it is demonstrated that the required energy is insensitive to pulse-duration variations (due to component changes). An easily synthesized suboptimal approximation is developed and requires only slightly more energy than the optimal pulse.
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The Mathematical Theory of Optimal Processes.
E. K. Blum, Pontryagin, Boltyanskii et al. · American Mathematical Monthly · 1963 · 4.3K citations
Toshio Utsunomiya · Terebijon Gakkai zasshi/Terebijon · 1970 · 498 citations · Full text
P. M. DeRusso, Ranadeep Roy, C. M. Close et al. · Journal of Applied Mechanics · 1966 · 312 citations · Full text
Pulse, digital and switching waveforms
F.H. Wells · Ultrasonics · 1966 · 254 citations