Nicotine protects against μ-opioid receptor antagonism by β-funaltrexamine: Evidence for nicotine-induced release of endogenous opioids in brain

A METHOD FOR DETERMINING LOSS OF PAIN SENSATION

F. E. D'Amour, Donn L. Smith · Journal of Pharmacology and Experimental Therapeutics · 1941 · 3.2K citations

Nursing, Pharmacology, Pain Management +14

Pharmacological characterization in vivo of the novel opiate, beta-funaltrexamine.

Susan J. Ward, Philip S. Portoghese, A.E. Takemori · Journal of Pharmacology and Experimental Therapeutics · 1982 · 302 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Development and maintenance of morphine tolerance and dependence in the rat by scheduled access to morphine drinking solutions.

Vance F. Gellert, Stephen G. Holtzman · Journal of Pharmacology and Experimental Therapeutics · 1978 · 268 citations

Medicine, Pharmacology, Behavioral Pharmacology +5

The irreversible narcotic antagonistic and reversible agonistic properties of the fumaramate methyl ester derivative of naltrexone

A.E. Takemori, Dennis L. Larson, Philip S. Portoghese · European Journal of Pharmacology · 1981 · 230 citations

Medicine, Medicinal Chemistry, Pharmacology +9

Nicotinic receptor stimulation activates enkephalin release and biosynthesis in adrenal chromaffin cells

Lee E. Eiden, Pierre Giraud, Jitendra R. Dave et al. · Nature · 1984 · 209 citations

Life Sciences, Neuroscience, Physiology +12