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A Diagnostic Quartet in Leptomeningeal Infiltration of the Optic Nerve Sheath
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1994
Year
PathologySurgeryOptic NerveRetinaVitreous BodyOptic Leptomeningeal CarcinomatosisLeptomeningeal CarcinomatosisOptic Nerve SheathNeurologyNeuropathologyOphthalmologyOcular PathologyLeptomeningeal InfiltrationNervous SystemOculoplasticsNeuroanatomyDiagnostic QuartetGlaucomaCentral Nervous SystemMedicine
A rare case of optic leptomeningeal carcinomatosis secondary to a rectal adenocarcinoma is recorded. The presentation of rectal disease with blindness is unique. A diagnostic quartet of symptoms and signs of leptomeningeal infiltration of the optic nerve sheath is proposed and its value emphasized by the inability of further investigation to confirm the clinical diagnosis. The investigation and treatment of leptomeningeal carcinomatosis is reviewed.