Controlled Radio-Frequency Generator for Production of Localized Heat in Intact Animal

Abstract

In our previous paper 1 we have shown that it is possible to produce differential heating in vitro in an electromagnetic field. his heating is dependent on the radio frequency, on the magnetic field strength, and on the coercive force of the magnetic particles of Fe 2 O 3 , which are 0.02μ-0.1μ in size and which serve as the target material. In this paper we will demonstrate that we can produce differential heating in the intact animal even to the point of localized tissue necrosis. Examples of the temperature changes in the normal tissues during treatment will be shown. We will describe the apparatus for recording this temperature and also the characteristics of the radio-frequency field used. The contribution of the electronic scientist in this medical research program has been threefold: First, it was necessary to develop a radio-frequency generator and work coil; second, several types of magnetic particles had