Interferon-α2b, with or without Prior Hepatic Artery Embolization: Clinical Response and Survival in Mid-Gut Carcinoid Patients: The Norwegian Carcinoid Study

Abstract

Interferon induced an objective response in mid-gut carcinoid patients as judged by the 24-h urinary 5-HIAA excretion. Patients receiving continuous interferon therapy showed improved response and survival compared with patients who stopped the treatment. Regardless of medical therapy, more survivors and more responders, as evaluated from CT measurements, were found among the embolized patients than among the non-embolized. Embolization could, however, not be shown to have a significant effect on survival.