Concepedia

Publication | Open Access

Statins impair glucose uptake in human cells

DOIFull Paper Access

48

Citations

27

References

2014

Year

Dominika Nowis, Agata Malenda, Karolina Furs, Bożenna Oleszczak, Radoslaw Sadowski, Justyna Chlebowska, Małgorzata Firczuk, Janusz M. Bujnicki, Adam D. Staruch, Radosław Zagożdżon,
BMJ Open Diabetes Research & Care

Abstract

Statins impair glucose uptake by cells involved in regulation of glucose homeostasis by inducing cholesterol-dependent conformational changes in GLUTs. This molecular mechanism might explain hyperglycemic effects of statins observed in clinical trials.

References

YearCitations

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