Persistent E-Cadherin Expression in Inflammatory Breast Cancer

Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role

Kris Vleminckx, L. Vakaet, M. Mareel et al. · Cell · 1991 · 1.7K citations

Life Sciences, Cell Biology, Molecular Biology +12

E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells.

U. Frixen, Jürgen Behrens, Matthew S. Sachs et al. · The Journal of Cell Biology · 1991 · 1.6K citations · Full text

Medicine, Cell Biology, Oncology +17

A causal role for E-cadherin in the transition from adenoma to carcinoma

Anne‐Karina T. Perl, Petra Wilgenbus, Ulf Dahl et al. · Nature · 1998 · 1.4K citations

Medicine, Cell Biology, Molecular Biology +12

E‐cadherin is a tumour/invasion suppressor gene mutated in human lobular breast cancers.

Geert Berx, Anne‐Marie Cleton‐Jansen, Friedel Nollet et al. · The EMBO Journal · 1995 · 775 citations

Medicine, Genetics, Oncology +12

E-cadherin is inactivated in a majority of invasive human lobular breast cancers by truncation mutations throughout its extracellular domain.

Geert Berx, Anne‐Marie Cleton‐Jansen, Kristin Strumane et al. · PubMed · 1996 · 470 citations

Medicine, Genetics, Oncology +12