The affinity of chlorhexidine for hydroxyapatite and tooth surfaces

Abstract

abstract – The aim of the present study was to investigate the possibility of increasing the adsorption of chlorhexidine to hydroxyapatite and teeth beyond the level observed for untreated material. For this purpose treatment of samples with 0.01 M glycerophosphate or phytic acid prior to the chlorhexidine adsorption was instituted. The results showed that phytic acid strongly enhanced the adsorption capacity of hydroxyapatite and teeth in vitro . Also, the release of the drug, upon elution with water, remained at a continuously higher level and exhibited longer duration in phytic acid–treated samples than in the other ones examined.